Hi
I'm having problems with both IE and my desktop. If I try and use IE7 after a short time I can't use the right click or left click, select the menu's or open new tabs. When I try to select Tools it selects the Home page icon but doesn't go to the homepage. When I then go to the desktop I can't open anything at all. The egg timer comes up when I doubleclick but nothing opens. I can't even use CTRL ALT DEL to bring up Task Manager. McAfee doesn't pick up any viruses, help!

Logfile of HijackThis v1.99.1
Scan saved at 14:48:13, on 30/09/2008
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v7.00 (7.00.6000.16705)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\wltrysvc.exe
C:\WINDOWS\System32\bcmwltry.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
C:\Program Files\Bonjour\mDNSResponder.exe
C:\WINDOWS\System32\svchost.exe
C:\PROGRA~1\McAfee\MSC\mcmscsvc.exe
c:\program files\common files\mcafee\mna\mcnasvc.exe
c:\PROGRA~1\COMMON~1\mcafee\mcproxy\mcproxy.exe
C:\PROGRA~1\McAfee\VIRUSS~1\mcshield.exe
C:\Program Files\McAfee\MPF\MPFSrv.exe
C:\Program Files\McAfee\MSK\MskSrver.exe
C:\WINDOWS\system32\nvsvc32.exe
C:\WINDOWS\system32\svchost.exe
C:\Program Files\iPod\bin\iPodService.exe
C:\PROGRA~1\McAfee\VIRUSS~1\mcsysmon.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\system32\Rundll32.exe
C:\WINDOWS\system32\wltray.exe
C:\Program Files\McAfee.com\Agent\mcagent.exe
C:\Program Files\iTunes\iTunesHelper.exe
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\Stardock\Impulse\Impulse.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\Documents and Settings\Rod\Desktop\HijackThis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://home.skysports.com/football/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant =
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,CustomizeSearch =
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Local Page =
R1 - HKCU\Software\Microsoft\Internet Connection Wizard,ShellNext = http://www.meshcomputers.com/
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = *.local
O2 - BHO: (no name) - {02478D38-C3F9-4efb-9B51-7695ECA05670} - (no file)
O2 - BHO: McAntiPhishingBHO - {377C180E-6F0E-4D4C-980F-F45BD3D40CF4} - c:\PROGRA~1\mcafee\msk\mcapbho.dll
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre1.6.0_05\bin\ssv.dll
O2 - BHO: scriptproxy - {7DB2D5A0-7241-4E79-B68D-6309F01C5231} - C:\Program Files\McAfee\VirusScan\scriptsn.dll
O3 - Toolbar: (no name) - {0BF43445-2F28-4351-9252-17FE6E806AA0} - (no file)
O4 - HKLM\..\Run: [P17Helper] Rundll32 SPIRun.dll,RunDLLEntry
O4 - HKLM\..\Run: [wltray.exe] C:\WINDOWS\system32\wltray.exe
O4 - HKLM\..\Run: [nwiz] rem nwiz.exe /install
O4 - HKLM\..\Run: [NvCplDaemon] rem RUNDLL32.EXE C:\WINDOWS\system32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [mcagent_exe] C:\Program Files\McAfee.com\Agent\mcagent.exe /runkey
O4 - HKLM\..\Run: [iTunesHelper] "C:\Program Files\iTunes\iTunesHelper.exe"
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - HKCU\..\Run: [ImpulseFastStart] "C:\Program Files\Stardock\Impulse\Impulse.exe" /fastload
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_05\bin\ssv.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_05\bin\ssv.dll
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - %windir%\Network Diagnostic\xpnetdiag.exe (file missing)
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - %windir%\Network Diagnostic\xpnetdiag.exe (file missing)
O9 - Extra button: PartyPoker.net - {F4430FE8-2638-42e5-B849-800749B94EED} - C:\WINDOWS\system32\shdocvw.dll
O9 - Extra 'Tools' menuitem: PartyPoker.net - {F4430FE8-2638-42e5-B849-800749B94EED} - C:\WINDOWS\system32\shdocvw.dll
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O10 - Unknown file in Winsock LSP: c:\program files\bonjour\mdnsnsp.dll
O11 - Options group: [INTERNATIONAL] International*
O14 - IERESET.INF: START_PAGE_URL=http://www.meshcomputers.com
O15 - Trusted Zone: http://*.mcafee.com
O16 - DPF: {164B406B-0FD6-4E7F-BA7E-64D227D4CA37} (dnlplayer Class) - http://www.digitalwebbooks.com/reader/dbplugin.cab
O16 - DPF: {1803B9EF-9905-4F34-AFC4-05D1BAB28801} (RegUserCfgUI Class) - http://us.dl1.yimg.com/download.yahoo.com/dl/controls/yregucfg/2005_6_10_1/yregucfg.cab
O16 - DPF: {39B0684F-D7BF-4743-B050-FDC3F48F7E3B} - http://www.fileplanet.com/fpdlmgr/cabs/FPDC_2.3.6.108.cab
O16 - DPF: {4C39376E-FA9D-4349-BACC-D305C1750EF3} (EPUImageControl Class) -
O16 - DPF: {4F1E5B1A-2A80-42CA-8532-2D05CB959537} (MSN Photo Upload Tool) - http://by133fd.bay133.hotmail.msn.com/resources/MsnPUpld.cab
O16 - DPF: {6E32070A-766D-4EE6-879C-DC1FA91D2FC3} (MUWebControl Class) - http://update.microsoft.com/microsoftupdate/v6/V5Controls/en/x86/client/muweb_site.cab?1161859589757
O16 - DPF: {8AD9C840-044E-11D1-B3E9-00805F499D93} (Java Runtime Environment 1.6.0) - http://javadl-esd.sun.com/update/1.6.0/jinstall-6u5-windows-i586-jc.cab
O16 - DPF: {A90A5822-F108-45AD-8482-9BC8B12DD539} (Crucial cpcScan) - http://www.crucial.com/controls/cpcScanner.cab
O16 - DPF: {C606BA60-AB76-48B6-96A7-2C4D5C386F70} (PreQualifier Class) - http://help.broadbandassist.com/bbdesktop/PreQual/files/MotivePreQual.cab
O16 - DPF: {D8089245-3211-40F6-819B-9E5E92CD61A2} (FlashXControl Object) - https://flashpoker.ladbrokes.com/Ladbrokes/FlashAX.cab
O20 - Winlogon Notify: WgaLogon - C:\WINDOWS\SYSTEM32\WgaLogon.dll
O21 - SSODL: WPDShServiceObj - {AAA288BA-9A4C-45B0-95D7-94D524869DB5} - C:\WINDOWS\system32\WPDShServiceObj.dll
O23 - Service: McAfee Application Installer Cleanup (0219741222773850) (0219741222773850mcinstcleanup) - McAfee, Inc. - C:\WINDOWS\TEMP\021974~1.EXE
O23 - Service: Apple Mobile Device - Apple Inc. - C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
O23 - Service: Bonjour Service - Apple Inc. - C:\Program Files\Bonjour\mDNSResponder.exe
O23 - Service: Canon Camera Access Library 8 (CCALib8) - Canon Inc. - C:\Program Files\Canon\CAL\CALMAIN.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\11\Intel 32\IDriverT.exe
O23 - Service: iolo FileInfoList Service (ioloFileInfoList) - Unknown owner - C:\Program Files\iolo\common\lib\ioloServiceManager.exe
O23 - Service: iolo System Service (ioloSystemService) - Unknown owner - C:\Program Files\iolo\common\lib\ioloServiceManager.exe
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: McAfee Services (mcmscsvc) - McAfee, Inc. - C:\PROGRA~1\McAfee\MSC\mcmscsvc.exe
O23 - Service: McAfee Network Agent (McNASvc) - McAfee, Inc. - c:\program files\common files\mcafee\mna\mcnasvc.exe
O23 - Service: McAfee Scanner (McODS) - McAfee, Inc. - C:\PROGRA~1\McAfee\VIRUSS~1\mcods.exe
O23 - Service: McAfee Proxy Service (McProxy) - McAfee, Inc. - c:\PROGRA~1\COMMON~1\mcafee\mcproxy\mcproxy.exe
O23 - Service: McAfee Real-time Scanner (McShield) - McAfee, Inc. - C:\PROGRA~1\McAfee\VIRUSS~1\mcshield.exe
O23 - Service: McAfee SystemGuards (McSysmon) - McAfee, Inc. - C:\PROGRA~1\McAfee\VIRUSS~1\mcsysmon.exe
O23 - Service: McAfee Personal Firewall Service (MpfService) - McAfee, Inc. - C:\Program Files\McAfee\MPF\MPFSrv.exe
O23 - Service: McAfee SpamKiller Service (MSK80Service) - McAfee, Inc. - C:\Program Files\McAfee\MSK\MskSrver.exe
O23 - Service: NMIndexingService - Nero AG - C:\Program Files\Common Files\Nero\Lib\NMIndexingService.exe
O23 - Service: NVIDIA Display Driver Service (NVSvc) - NVIDIA Corporation - C:\WINDOWS\system32\nvsvc32.exe
O23 - Service: SiSoftware Deployment Agent Service (SandraAgentSrv) - SiSoftware - C:\Program Files\SiSoftware\SiSoftware Sandra Professional Business XII.SP2c\RpcAgentSrv.exe
O23 - Service: ServiceLayer - Nokia. - C:\Program Files\PC Connectivity Solution\ServiceLayer.exe
O23 - Service: SupportSoft Sprocket Service (O2) (sprtsvc_O2) - Unknown owner - C:\Program Files\O2\bin\sprtsvc.exe" /service /p O2 (file missing)
O23 - Service: SupportSoft RemoteAssist - SupportSoft, Inc. - C:\Program Files\Common Files\Supportsoft\bin\ssrc.exe
O23 - Service: Broadcom Wireless LAN Tray Service (wltrysvc) - Unknown owner - C:\WINDOWS\System32\wltrysvc.exe

Thanks
Rod